คำตอบชัดๆ น่าจะอยู่ในคำตอบของ René Dudfield

we did a prototype of a flex-pypy(and then continued ) - which uses
pypy to translate into actionscript - which is then compiled with the
free flex compiler. So the 'bash the monkey' thing on the pygame main
page is made with that.

However... flex and pypy are such un-fun things to use that I think it
would require someone to be paid to work on it to get it
finished(think not one, but two compile steps... one using java!
eeewww) . If there's anyone who wants to pay for it, I think a pretty
could port could be done in less than 3 months. It would still be
buggy, but you could probably get many pygame games working on flash.
The idea is to implement the pygame API using flash. Yes, flash 8+
can do fast blits. You can kind of emulate basic blitting with flash
7 too.